発生生物学研究室│埼玉大学大学院理工学研究科生命科学部門 理学部生体制御学科

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研究業績

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原著論文(1998年以降)

各教員の研究業績:[弥益][川村][津田]

Tatsuya Yuikawa, Masaaki Ikeda, Sachiko Tsuda, Shinji Saito, Kyo Yamasu
Involvement of Oct4-type transcription factor Pou5f3 in posterior spinal cord formation in zebrafish embryos
Develop. Growth Differ. 63:306−322 (2021)[PubMed]

Yamada K*, Maeno A*, Araki S, Kikuchi M, Suzuki M, Ishizaka M, Satoh K, Akama K, Kawabe Y, Suzuki K, Kobayashi D,
Hamano N, and Kawamura A  (*These authors equally contributed to this work)
An atlas of seven zebrafish hox cluster mutants provides insights into sub/neofunctionalization of vertebrate Hox clusters 

Development, 148(11): dev198325 (2021) [Pubmed]  

Kazuki Takahashi, Yuki Ito, Mami Yoshimura, Masataka Nikaido, Tatsuya Yuikawa, Akinori Kawamura, Sachiko Tsuda, Daichi Kage, Kyo Yamasu
A globin-family protein, Cytoglobin 1, is involved in the development of neural crest-derived tissues and organs in zebrafish
Dev. Biol. 472:1-17 (2021)[PubMed]

C. Inomata, T. Yuikawa, Y. Nakayama-Sadakiyo, K. Kobayashi, M. Ikeda, M. Chiba, C. Konishi, A. Ishioka, S. Tsuda, and K. Yamasu
Involvement of an Oct4-related PouV gene, pou5f3/pou2, in neurogenesis in the early neural plate of zebrafish embryos.
Dev. Biol. 457:30-42 (2020)[PubMed]

Akama K, Ebata K, Maeno A, Taminato T, Otosaka S, Gengyo-Ando K, Nakai J, Yamasu K, and Kawamura A

The role of somite patterning in the formation of Weberian apparatus and pleural rib in zebrafish.

Journal of Anatomy 236(4): 622-629 (2020) [Pubmed]

Ban H, Yokota D, Otosaka S, Kikuchi M, Kinoshita H, Fujino Y, Yabe T, Ovara H, Izuka A, Akama K, Yamasu K, Takada S, and Kawamura A Transcriptional autoregulation of zebrafish tbx6 is required for somite segmentation.

Development in press (2019) [Pubmed]

Fujino Y, Yamada K, Sugaya C, Ooka Y, Ovara H, Ban H, Akama K, Otosaka S, Kinoshita H, Yamasu K, Mishima Y and Kawamura A
Deadenylation by CCR4-NOT complex contributes to the turnover of hairy-related mRNAs in zebrafish segmentation clock.
FEBS Letters, 592:3388-3398 (2018)[PubMed]

Sachiko Tsuda, Kanae Hiyoshi, Hiroaki Miyazawa, Risa Kinno, & Kyo Yamasu
4D imaging identifies dynamic migration and the fate of gbx2-expressing cells in the brain primordium of zebrafish.
Neurosci. Lett. 690:112-119 (2018)[PubMed]

K. Okumura, H. Kakinuma, R. Amo, H. Okamoto, K. Yamasu, & S. Tsuda
Optical measurement of neuronal activity in the developing cerebellum of zebrafish using voltage-sensitive dye imaging.
Neuroreport 29:1349−1354 (2018)[PubMed]

Hirofumi Kinoshita, Nanae Ohgane, Yuuri Fujino, Taijiro Yabe, Hiroki Ovara, Daisuke Yokota, Ayaka Izuka, Daichi Kage, Kyo Yamasu, Shinji Takada, Akinori Kawamura
Functional roles of the Ripply-mediated suppression of segmentation gene expression at the anterior presomitic mesoderm in zebrafish.
Mech. Dev. 152:21-31 (2018)[PubMed]

H. Miyazawa, K. Okumura, K. Hiyoshi, K. Maruyama, H. Kakinuma, R. Amo, H. Okamoto, K. Yamasu, and S. Tsuda
Optical interrogation of neuronal circuitry in zebrafish using genetically encoded voltage indicators.
Sci. Rep. 8, 6048 (2018)[PubMed]

M. Nikaido, S. Izumi, H. Ohnuki, Y. Takigawa, K. Yamasu, K. Hatta
Early development of the enteric nervous system visualized by using a new transgenic zebrafish line harboring a regulatory region for choline acetyltransferase a (chata) gene.
Gene Expr. Patterns 28, 12-21 (2018)[PubMed]

K. Kobayashi, A. Khan, M. Ikeda, A. Nakamoto, M. Maekawa, and K. Yamasu
In vitro analysis of the transcriptional regulatory mechanism of zebrafish pou5f3.
Exp. Cell Res. 364, 28-41 (2018)[PubMed]

Z. Wang, Y. Nakayama, S. Tsuda, and K. Yamasu
The role of gastrulation brain homeobox 2 (gbx2) in the development of the ventral telencephalon in zebrafish embryos.
Differentiation 99, 28-40 (2018) [PubMed]

Yukiko Nakayama, Chihiro Inomata, Tatsuya Yuikawa, Sachiko Tsuda, and Kyo Yamasu
Comprehensive analysis of target genes in zebrafish embryos reveals gbx2 involvement in neurogenesis.
Dev. Biol. 430, 237-248 (2017) [PubMed]

Taminato T, Yokota D, Araki S, Ovara H, Yamasu K, Kawamura A.
Enhancer activity-based identification of functional enhancers using zebrafish embryos.
Genomics. 108,102-107 (2016) [PubMed]>

Akinori Kawamura, Hiroki Ovara, Yuko Ooka, Hirofumi Kinoshita, Miki Hoshikawa, Kenji Nakajo, Daisuke Yokota, Yuuri Fujino, Shin-ichi Higashijima, Shinji Takada, Kyo Yamasu
Posterior-anterior gradient of zebrafish hes6 expression in the presomitic mesoderm is established by the combinatorial functions of the downstream enhancer and 3′UTR.
Dev. Biol. 130, 532-552 (2016) [PubMed]

Kim, J., Lee, S., Tsuda, S., Zhang, X., Chow, N., Namburi, P., Kee, M., Cunha, C., Gloss, B., Feng, G., Augustine, G.J.
Optogenetic mapping of local inhibitory circuitry in cerebellum reveals spatial coordination of interneurons via electrical synapses.
Cell Rep. Vol. 7(5), 1601-13 (2014)[PubMed]

Yukiko Nakayama, Hiroshi Kikuta, Maiko Kanai, Kimihito Yoshikawa, Akinori Kawamura, Kana Kobayashi, Zhe Wang, Alam Khan, Koichi Kawakami, and Kyo Yamasu
Gbx2 functions as a transcriptional repressor to regulate the specification and morphogenesis of the mid-hindbrain junction in a dosage- and stage-dependent manner.
Mech. Dev. 130, 532-552 (2013) [PubMed]

A.Khan, A. Nakamoto, S. Okamoto, M. Tai, Y. Nakayama, K. Kobayashi, A. Kawamura, H. Takeda, and K. Yamasu
Pou2, a class V POU-type transcription factor in zebrafish, regulates dorsoventral patterning  and convergent extension movement at different blastula stages
Mech. Dev. 129, 219-235 (2012) [PubMed]

A. Khan, A. Nakamoto, M. Tai, S. Saito, Y. Nakayama, A. Kawamura, H. Takeda, and K. Yamasu
Mesendoderm specification depends on the function of Pou2, the class V POU-type transcription factor, during zebrafish embryogenesis
Develop. Growth Differ. 54, 686-701 (2012) [PubMed]

M. Saito, K. Yamasu, & T. Suyemitsu
Binding properties of thyroxine to nuclear extract from sea urchin larvae.
Zool. Sci.29, 79-82 (2012) [PubMed]

A. Ishioka, T. Jindo, T. Kawanabe, K. Hatta, M. S. Parvin, M. Nikaido, Y. Kuroyanagi, H. Takeda, and K. Yamasu
Retinoic acid-dependent establishment of positional information in the hindbrain was conserved during vertebrate evolution.
Dev. Biol. 350, 154-168 (2011) [PubMed]

T. Okubo, A. Kawamura, J. Takahashi, H, Yagi, M. Morishima, R. Matsuoka, and S. Takada
Ripply3, a Tbx1 repressor, is required for development of pharyngeal apparatus and its derivatives in mice
Development 138, 339-348 (2011) [PubMed]

S. Ota, N. Tonou-Fujimori, Y. Nakayama, Y. Ito, A. Kawamura, and K. Yamasu
FGF receptor gene expression and its regulation by FGF signaling during early zebrafish development.
Genesis. 48, 707-716 (2010) [PubMed] <Cover Image>

S. Ota, N. Tonou-Fujimori, and K. Yamasu
The roles of the FGF signal in zebrafish embryos analyzed using constitutive activation and dominant-negative suppression of different FGF receptors.
Mech. Dev. 126, 1-17 (2009)[PubMed]

M. S. Parvin, N. Okuyama, F. Inoue, M. E. Islam, A. Kawakami, H. Takeda, & K. Yamasu
An autoregulatory loop and retinoic acid repression regulate pou2/pou5f1 gene expression in the zebrafish embryonic brain.
Dev. Dyn. 237, 1373-1388 (2008) [PubMed]

A. Kawamura, S. Koshida, & S. Takada
Activator-to-repressor conversion of T-box transcription factors by the Ripply family of Groucho/TLE-associated mediators.
Mol. Cell. Biol. 28, 3236-3244 (2008) [PubMed]

F. Inoue, M. S. Parvin, & K. Yamasu
Transcription of fgf8 is regulated by activating and repressive cis-elements at the midbrain-hindbrain boundary in zebrafish embryos.
Dev. Biol. 316, 471-486 (2008) [PubMed]

M. Nikaido, K. Doi, T. Shimizu, M. Hibi, Y. Kikuchi, & K. Yamasu
Initial specification of the epibranchial placode in zebrafish embryos depends on the fibroblast growth factor signal.
Dev. Dyn. 236, 564-571 (2007) [PubMed]

M. E. Islam, H. Kikuta, F. Inoue, M. Kanai, A. Kawakami, M. S. Parvin, H. Takeda, & K. Yamasu
Three enhancer regions regulate gbx2 gene expression in the isthmic region during zebrafish development.
Mech. Dev. 123, 907-924 (2006)[PubMed]

F. Inoue, S. Nagayoshi, S. Ota, M. E. Islam, N. Tonou-Fujimori, Y. Odaira, K. Kawakami, & K. Yamasu
Genomic organization, alternative splicing, and multiple regulatory regions of the zebrafish fgf8 gene.
Develop. Growth & Differ. 48, 447- 62 (2006)[PubMed]

H. Kikuta, M. Kanai, Y. Ito, & K. Yamasu
gbx2 homeobox gene is required for the maintenance of the isthmic region in the zebrafish embryonic brain.
Dev. Dyn. 228, 433-450 (2003)[PubMed]

K. Horii, G. Suzuki, T. Suyemitsu, & K. Yamasu
Characterization of the upstream region that regulates the transcription of the gene for the precursor to EGF-related peptides, exogastrula-inducing peptides, of the sea urchin Anthocidaris crassispina.
Comp. Biochem. Physiol. B Biochem. Mol. Biol. 136, 15-26 (2003)[PubMed]

Y. Hirate, H. Okamoto, & K. Yamasu
Structure of the zebrafish fasciclin I-related extracellular matrix protein (big-h3) and its characteristic expression during embryogenesis.
Gene Expr. Patterns 3, 331-336 (2003)[PubMed]

A. F. Giusti, F. J. O'Neill, K. Yamasu, K. R. Foltz, & L. A. Jaffe
Function of a sea urchin egg src family kinase in initiating Ca2+ release at fertilization.
Dev. Biol. 256, 367-378 (2003)[PubMed]

N. Tonou-Fujimori, M. Takahashi, H. Onodera, H. Kikuta, S. Koshida, H. Takeda & K. Yamasu
Expression of the FGF receptor 2 gene (fgfr2) during embryogenesis in the zebrafish Danio rerio.
Mech. Dev. 119, Suppl 1, S173-178 (2002)[PubMed]

Y. Haruguchi, K. Horii, G. Suzuki, T. Suyemitsu, K. Ishihara, & K. Yamasu
Genomic organization of the gene that encodes the precursor to EGF-related peptides, exogastrula-inducing peptides, of the sea urchin Anthocidaris crassispina.
Biochim. Biophys. Acta
1574, 311-320 (2002)[PubMed]

K. Tomita, K. Yamasu, & T. Suyemitsu
Role of syndecan in the elongation of postoral arms in sea urchin larvae.
Develop. Growth & Differ. 44, 45-53 (2002)[PubMed]

Y. Hirate, M. Mieda, T. Harada, K. Yamasu, & H. Okamoto
Identification of ephrin-A3 and novel genes specific to the midbrain-MHB in embryonic zebrafish by ordered differential display.
Mech. Dev. 107, 83-96 (2001) [PubMed]

K. Yamasu, G. Suzuki, K. Horii, & T. Suyemitsu
Transcriptional regulation of the gene for epidermal growth factor-like peptides in sea urchin embryos.
Int. J. Dev. Biol. 44, 777-784 (2000) [PubMed]

K. Tomita, K. Yamasu, & T. Suyemitsu
Cloning and characterization of the cDNA for syndecan core portein in sea urchin embryos.
Develop. Growth & Differ. 42, 449-458 (2000) [PubMed]

A. Sawada, A. Fritz, Y.-J. Jiang, A. Yamamoto, K. Yamasu, A. Kuroiwa, Y. Saga & H. Takeda
Zebrafish Mesp family genes, mesp-a and mesp-b are segmentally expressed in the presomitic mesoderm, and Mesp-b confers the anterior identity to the developing somites.
Development 127, 1691-1702 (2000) [PubMed]

M. Saito & K. Yamasu
Expression of the gene for translation elongation factor 1a-related protein during development of the sea urchin Anthocidaris crassispina.
Zool.Sci.
16, 785-792 (1999) [J stage]

Y. Hirate, K. Tomita, S. Yamamoto, K. Kobari, I. Uemura, K. Yamasu, & T. Suyemitsu
Association of the sea urchin EGF-related peptide, EGIP-D, with fasciclin I related ECM proteins from the sea urchin Anthocidaris crassispina.
Develop. Growth & Differ.
41, 483-494 (1999) [PubMed]

H. Onodera, K. Kobari, M. Sakuma, M. Sato, T. Suyemitsu, & K. Yamasu
Expression of a src-type protein tyrosine kinase gene, AcSrc1, in the sea urchin embryo.
Develop. Growth & Differ. 41, 19-28 (1999) [PubMed]

K. Yamasu & F. H. Wilt
The functional organization of DNA elements regulating SM30a, a spicule matrix gene of sea urchin embryos.
Develop.Growth & Differ. 41, 81-91 (1999) [PubMed]

M. Saito, M. Seki, S. Amemiya, K. Yamasu, T. Suyemitsu, & K. Ishihara
Induction of metamorphosis in the sand dollar Peronella japonica by thyroid hormones.
Develop. Growth & Differ. 40, 307-312 (1998) [PubMed]

総 説

新屋みのり、武田洋幸、弥益 恭
ゼブラフィッシュから見た脊椎動物の神経誘導と中枢神経系の前後軸に沿ったパターン形成機構
蛋白質 核酸 酵素, 45, 2766-2774 (2000)

著書(翻訳)

塩尻信義、弥益 恭、加藤容子、中尾啓子(共編著)
発生生物学 基礎から応用への展開
裳華房(2019)

弥益 恭、中尾啓子、野口 航(共編著)
新しい生物科学
培風館(2018)

弥益 恭
ゼブラフィッシュの発生遺伝学
裳華房(2015)

弥益 恭(編集及び執筆分担)
生物の事典(石原勝敏、末光隆志総編集)、朝倉書店(2010)

石原・浅尾・団・山口・弥益著
目で見る生物学(三訂版) 培風館(2006)

F.H.Wilt & S.C.Hake、赤坂・大隅・八杉監訳(弥益分担訳)
ウィルト発生生物学、東京化学同人 (2006)

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